Long Term Remission of a Primary Intracerebral Hodgkin Lymphoma in a Patient Previously Treated With Azathioprine

Primary central nervous system (CNS) lymphoma is a rare form of primary brain neoplasm, in which ninety percent of cases are diffuse large B-cell lymphoma. HL involving the CNS is a rare event happening most of them in the context of relapsed systemic disease [1,2]. Primary CNS-hodgkin lymphoma (CNS-HL) is very rare, occurring in less than 0.2% of all HL cases [3], and it has been poorly reported in the literature. Most of these few published cases refer to human immunodeficiency virus (HIV) patients [4,5]. Immunosuppressive therapy like azathioprine carries a well reported increase risk of developing lymphoma [3].